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REVIVO BioSystems' Chronological Aging Model wins Outstanding Innovation Award


[October 2024 Edition]


REVIVO BioSystems at COSMETIC 360 in Paris 


This past October we had a successful wrap-up of the COSMETIC 360 event in Paris, France. Connecting with so many industry professionals passionate about advancing skincare and cosmetic science made this event a remarkable experience for us at REVIVO BioSystems.



The highlight of the event was our Chronological Aging Skin Model winning the Outstanding Innovation Award in the Testing & Analysis category. This recognition underscores our ongoing commitment to pioneering effective and innovative solutions for your skincare research. 



Thank you to  everyone who visited, connected, and shared ideas with us.  We look forward to continuing these conversations and exploring new collaborations. 

Reach out to info@revivobio.com to find out more about collaborating with us. 


Why the Chronological Ageing Model an is an Outstanding Innovation 


In vitro skin models help us to understand the mechanisms of aging, advancing the development of innovative treatments and skin care interventions. 


While informative, traditional in vitro models present limitations in reproducing natural biological expressions of significant proteins and gene expressions. This can hinder their ability to provide realistic insights into skin-related phenomena. 

With REVIVO BioSystems’ 4D in vitro tissue models that leverage our dynamic organ-on-a-chip technology, these skin models closely resemble native human skin where significant proteins and genes, closer to natural levels in native tissues, are expressed. 


Our Chronological Aging Skin Model is able to mimic chronological aging independently of oxidative stress, offering a more nuanced insight into the aging process of the skin. It is ready in a 'healthy' and 'youthful' state, allowing the aging process to unfold over time.


Why is this a game-changer?


Following the aging process, it is easy to observe significant reduction in epidermal thickness (see below image) in the aged 4D skin model, and noticeable significant changes to the expression of a youth marker and proliferation. In contrast, when skin models are reconstructed in static  cell culture inserts, they already exhibit certain age-related characteristics such as low expression of youth and proliferation markers. As a result, their potential to provide an appropriate and accurate model for distinct anti-ageing product claims can be limited.

Explore further our Chronological Ageing Model and its applications on our website.


For enquiries, reach out to our team of experts at sales@revivobio.com


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