Why choose the 4D?
While in vitro 3D cell culture models capture certain aspects of human tissue physiology, they fall short in replicating the realistic movement of nutrients and waste products within tissues. This limitation hinders their ability to create accurate environments for unique product claims.
Here's how our 4D technology takes center stage. The dynamic 4D system comprises small channels that mimic the flow of blood underneath the skin tissues, resulting in a natural tissue environment that closely resembles in-vivo-like physiological conditions. The expression of essential biomarkers undergoes significant and observable changes, offering a clear insight into the aging process and the effect of your skin treatment
Testing of new substances is carried out with enhanced accuracy and effectiveness, surpassing the capabilities of static tissue models that do not replicate the dynamic aspects of blood flow.
Our Key Highlights
FINE-TUNED COMPOUND DELIVERY
Sustained and pulsed delivery of stress factors, hormones, drugs, and other compounds of interest to interfere with tissue physiology during the tissue treatment/conditioning
Enables more comprehensive studies by examining the soluble factors released by the skin into the media over time, achieved through the automated collection and analysis of the outflow.
LONG-TERM EPITHELIUM STUDIES
Recreates epithelium differentiation while also maintaining the viability of keratinocytes, which allows for long-term studies.
Our 4D in-vitro testing enables more efficient translation of experimental findings from preclinical research to your clinical development.
How does the 4D technology compare to 3D in vitro platforms?
How does it work?
Alexa Young, PhD,.......
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